What is a Lenalidomide?
Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes.
For multiple myeloma, it is used after at least one other treatment and generally with dexamethasone. It is taken by mouth.
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Is lenalidomide safe?
Lenalidomide can cause birth defects in children. So you must not become pregnant or father a child while taking this drug.
Your doctor will talk to you about effective methods of contraception before you have the treatment. Some people worry about taking lenalidomide but it doesn’t cause physical defects in adults.
How successful is lenalidomide?
Among patients in the lenalidomide plus rituximab versus placebo plus rituximab groups, the rate of best overall response assessed by IRC was 78% (95% CI, 71% to 83%) versus 53% (95% CI, 46% to 61%; P < . 0001), with 34% (95% CI, 27% to 41%) versus 18% (95% CI, 13% to 25%) of patients achieving CR (P = .
What is the side effect of lenalidomide?
Lenalidomide may cause a serious type of reaction called tumor lysis syndrome. Call your doctor right away if you have a decrease or change in urine amount, joint pain, stiffness, or swelling, lower back, side, or stomach pain, a rapid weight gain, swelling of the feet or lower legs, or unusual tiredness or weakness.
How long can you take lenalidomide?
Adults—At first, 20 milligrams (mg) once a day. This medicine is taken on Days 1 to 21 of repeated 28-day cycles for up to 12 cycles. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.
Does lenalidomide affect the kidneys?
In conclusion, renal failure is an uncommon, but serious, potential complication of lenalidomide therapy in plasma cell dyscrasias in general, particularly in MM. In both cases reported here, renal function was aggravated during the first cycle of therapy with the drug employed.
Is lenalidomide a chemo drug?
Chemotherapy drugs, such as lenalidomide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Daratumumab-hyaluronidase is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread.