How To Avoid Systemic Absorption Of Eye Drops

Avoiding systemic absorption of eye drops is important, especially for medications like beta-blockers (e.g., timolol), steroids, or anticholinergics, which can have side effects beyond the eyes (like affecting heart rate, breathing, or causing dry mouth). Fortunately, a simple technique can drastically reduce this risk.

✅ Steps to Avoid Systemic Absorption of Eye Drops

👁️ 1. Use the Correct Drop Technique

Wash hands before applying.
Tilt your head back, look up, and gently pull down the lower eyelid to create a pocket.
Drop the medication into the pocket, not directly onto the eyeball.

✋ 2. Apply Gentle Pressure to the Inner Corner of the Eye (Punctal Occlusion)

Immediately after applying the drop, press gently on the inner corner of your eye (near the nose) with your index finger.
This closes the nasolacrimal duct, which connects your eye to your nose and bloodstream.
Hold the pressure for 1–2 minutes per eye.
This is the most effective way to minimize systemic absorption.

🧻 3. Blot Excess Medication

Use a clean tissue to wipe away any excess that spills out of the eye.
Do not blink excessively or rub your eye — it may push medication into the drainage system.

⏱️ 4. Wait Between Drops if Using Multiple Medications

If using more than one eye drop, wait at least 5 minutes between different drops.
This prevents overflow and ensures each medication is absorbed properly in the eye.

🚫 5. Avoid Overuse

Use the prescribed amount — more drops don’t help and increase risk of systemic absorption.
Most eyes can only hold one drop at a time.

⚠️ 6. Be Cautious if You Have Certain Health Conditions

If you have asthma, bradycardia, heart block, or other systemic health concerns, tell your doctor. They may choose eye drops with a lower risk of systemic effects.

🧠 Bonus Tip:

Ask your pharmacist if your eye drop comes in a gel or ointment form — these tend to stay localized in the eye longer and may reduce systemic exposure.