By | May 22, 2025

How To Avoid JC Virus

The JC virus (JCV) is a common virus that many people carry without symptoms. However, it can cause a rare and serious brain infection called progressive multifocal leukoencephalopathy (PML) in people with weakened immune systems.

Here’s how to reduce the risk of JC virus activation and infection:

What is JC Virus?

  • A widespread virus; about 50-80% of adults have been exposed.
  • Usually harmless unless immune system is severely weakened.
  • Reactivation can cause PML, especially in people on certain immunosuppressive treatments.

How to Avoid JC Virus Activation

1. Maintain a Healthy Immune System

  • Manage chronic diseases well (e.g., HIV, autoimmune diseases).
  • Avoid immunosuppressive drug overuse unless prescribed.
  • Eat a balanced diet, exercise regularly, get enough sleep.

2. Use Immunosuppressive Medications Carefully

  • If you’re on medications like natalizumab, rituximab, or other immune modulators, follow your doctor’s monitoring closely.
  • Doctors often test for JC virus antibodies before starting certain therapies.
  • Discuss alternatives if you test positive for JCV.

3. Practice Good Hygiene

  • JC virus spreads through bodily fluids (urine, saliva, possibly respiratory secretions).
  • Wash hands regularly.
  • Avoid sharing personal items like towels or toothbrushes.

4. Regular Medical Monitoring

  • If you have a weakened immune system or take immunosuppressive drugs, get regular check-ups.
  • Report any neurological symptoms early (weakness, vision problems, speech issues).

5. Avoid Exposure to Potential Triggers

  • Minimize contact with people who have active infections.
  • Stay up-to-date with vaccines for other infections.

Summary

Prevention StepWhy It Helps
Keep immune system strongPrevents virus reactivation
Monitor immunosuppressive therapyReduces risk of PML
Practice hygieneLimits viral spread
Regular medical careEarly detection and intervention